I bought this bag years back and it has served me well and stood up to abuse.
Pros up front:
Excellent durability. My wife cleaned mine, possibly with a pressure washer, and it came out looking almost brand new after years of me kicking it around.
The organization is pretty good depending on what exactly you want to set it up for.
Three large windowed pouches and three sort of tubular mesh pouches give you numerous options for arrangement, especially since both "sides" of the main pocket will accept the velcro on the back of the bags.
So, you can have pockets facing each other when the bag is closed and laid out in front of you when it's open. It's kind of a nice mix between a pack and a NAR sheet-bag style medic kit.
The windowed bags allow you to know how much of what you have pretty much at a glance.
The upper pouch, with it's own zipper, flops back like a Pez dispenser's head, but to a full 180° allowing fast and easy access to whatever you put on the top of the bag and there's a mesh tube organizer for that area and a "receiving area" for the mounting velcro. Great for oddly shaped items like a stethoscope too.
The exterior sleeve pouch on the back of the bag is great for large flat objects, chest seals and the like.
Everything about the bag is high quality. The zippers are almost impossible to blow out, stitching is good across the unit, the plastic on the windowed bags doesn't degrade and that hook/loop lasts very well.
Another note on the zippers, even if you stuff the bag full to the point you need to put a knee on it to close the zipper it will hold and the zips still open shockingly easily, even if closing the bag is a PITA. They're very high quality and they open fast in the correct direction.
This bag is also reasonably slim and packs flat and nearly square which makes it easy to store/play tetris with in a vehicle as long as you don't get the shock cord caught on anything.
The built in exterior shear holster is a nice touch and well placed, as are the zippers on the shoulder straps for running your hydration tube or some wires while reducing snag hazards.
Oh, and it's comfortable too.
Cons:
Price, obviously. I bought this bag quite some time ago and I believe it was <$400 at the time.
Stability: The bag generally wants to be laid down and opened, it doesn't want to stand up. To some degree this defeats the 180° opening of the top pouch unless you lean the bag against something or it's on someone else's back. Consider this when packing the bag, not when you're actually using it for real. You can peal out the mesh pouch in the top slot pretty easily but, depending on the situation, you may not want to.
Size: It's a medic's assault pack, which kind of narrows its application to some degree. It's not large and in charge like a 1000cc CCRK or the ARK nor is it super compact. At this price point, you may not be able to justify this bag unless you have a slot specific to its design.
Related to this, it can be a bit of a PITA if you're looking for that do-it-all bag. IV bags will consume space in this thing fast. It does have MOLLE on the sides, so dedicated IV bags could be added but I haven't seen any that truly fit the bill and the bag at the same time (hint, hint TacMed).
Also related to this, if you're really trying to max the bag the windowed pouches can produce a situation where it's not exactly clear which pouch is desired if you don't add a labeling system to them. This can be a problem if you're directing someone else to get you something and they don't know the bag's layout like you do. A colored highlight around the clear window would be an excellent added touch.
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Bottom line:
Tough as nails, it's a fantastic bag if you have a use-case for it but at the current price point you want to make sure that you do have that specific use-case.
It's a great bag, as designed, as a assault medic bag. It's also good for packing into a vehicle while bringing way more capability and capacity than an IFAK or even a squad kit bag but, as is, it's not going to give you the capacity of a larger bag or some of the capabilities, but then it won't take up the space either.
Use it in the right niche and it will serve you extremely well. If you have that niche, she's Goldilocks. I wouldn't sell or trade mine away but when it's closing in on $900 for just the bag I can't give it five stars.